http://www.informaworld.com/smpp/title~content=t713698011~db=all informaworld: articles recently published in Xenobiotica Informa Healthcare Articles recently published in Xenobiotica RSS feed of the most recently published articles of Xenobiotica 2009-12-01 undefined Xenobiotica 0049-8254 weekly 1 2009-12-01T00:00+00:00 Transport and metabolism of the antitumour drug candidate 2'-benzoyloxycinnamaldehyde in Caco-2 cells http://www.informaworld.com/smpp/content~content=a917087610~db=all~jumptype=rss Kim, H. M. Kwon, M. -G. Lee, C. W. Kang, J. S. Lee, K. S. Oh, S. J. Ryu, J. Yu, H. E. Kim, K. Kwon, B. -M. Park, S. -K. Lee, K. 39 12 881 888 Altered expression of CYP in TSOD mice: a model of type 2 diabetes and obesity http://www.informaworld.com/smpp/content~content=a917052883~db=all~jumptype=rss Sugiyama, K. Kudo, T. Shimada, T. Toda, T. Igeta, S. Suzuki, W. Ikarashi, N. Ochiai, W. Ito, K. Aburada, M. 39 12 889 902 C-7 configuration as one of determinants in taxanes metabolism by human cytochrome P450 enzymes http://www.informaworld.com/smpp/content~content=a917088234~db=all~jumptype=rss Yang, L. Sun, J. Wang, L. -M. Liu, H. -X. Ge, G. -B. Zhang, J. -W. Liu, Y. Zhang, Y. -Y. 39 12 903 914 Characterization of the porcine constitutive androstane receptor (CAR) and its splice variants http://www.informaworld.com/smpp/content~content=a917087834~db=all~jumptype=rss Squires, E. J. Peacock, J. N. Gray, M. A. 39 12 915 930 Influence of the MDR1 haplotype and CYP3A5 genotypes on cyclosporine blood level in Chinese renal transplant recipients http://www.informaworld.com/smpp/content~content=a917087831~db=all~jumptype=rss Cai, W. Yu, Z. Li, J. Jin, Z. Fang, J. Zhang, W. Chen, B. 39 12 931 938 Inter-individual difference determinant of prednisolone pharmacokinetics for Japanese renal transplant recipients in the maintenance stage http://www.informaworld.com/smpp/content~content=a917087770~db=all~jumptype=rss Satoh, S. Habuchi, T. Saito, M. Kagaya, H. Inoue, K. Miura, M. 39 12 939 945 Effects of Escherichia coli lipopolysaccharide on the metformin pharmacokinetics in rats http://www.informaworld.com/smpp/content~content=a917087836~db=all~jumptype=rss Lee, M. G. Kim, S. H. Choi, Y. H. Cho, Y. K. 39 12 946 954 Effects of diammonium glycyrrhizinate on the pharmacokinetics of aconitine in rats and the potential mechanism http://www.informaworld.com/smpp/content~content=a917087767~db=all~jumptype=rss Liu, X. -Q. Wang, J. -P. Chen, Y. -X. Davey, A. K. Yang, J. Chen, L. 39 12 955 963 Cross-species comparisons of the pharmacokinetics of ibudilast http://www.informaworld.com/smpp/content~content=a917087617~db=all~jumptype=rss Johnson, K. W. Gaeta, F. C. A. Suzuki, B. M. Gross, M. I. Gibbons, J. A. Sanftner, L. M. 39 12 964 977 Acknowledgements http://www.informaworld.com/smpp/content~content=a917088193~db=all~jumptype=rss 39 12 978 979 Prediction of Phase I single-dose pharmacokinetics using recombinant cytochromes P450 and physiologically based modelling http://www.informaworld.com/smpp/content~content=a913928037~db=all~jumptype=rss Gibson, C. R. Bergman, A. Lu, P. Kesisoglou, F. Denney, W. S. Mulrooney, E. 39 9 637 648 Species differences for stereoselective metabolism of ethofumesate and its enantiomers in vitro http://www.informaworld.com/smpp/content~content=a913867802~db=all~jumptype=rss Zhou, Z. Zhu, W. Dang, Z. Qiu, J. Lv, C. Liu, Y. Diao, J. 39 9 649 655 Comparison of intrinsic metabolic clearance in fresh and cryopreserved human hepatocytes http://www.informaworld.com/smpp/content~content=a913926909~db=all~jumptype=rss Hewitt, N. J. Hoogstraate, J. Johansson, J. Floby, E. Sohlenius-Sternbeck, A. -K. Hill, J. 39 9 656 662 Cytochrome P450-catalysed arene-epoxidation of the bioactive tea tree oil ingredient p- cymene: indication for the formation of a reactive allergenic intermediate? http://www.informaworld.com/smpp/content~content=a913928019~db=all~jumptype=rss Meesters, R. J. W. Duisken, M. Hollender, J. 39 9 663 671 CYP1A2 is the major isoform responsible for paeonol O -demethylation in human liver microsomes http://www.informaworld.com/smpp/content~content=a913867754~db=all~jumptype=rss He, Y. -Q. Yang, L. Li, W. Liu, H. -X. Hu, Y. Liu, Y. 39 9 672 679 Flavin-containing monooxygenase 1-catalysed N , N -dimethylamphetamine N -oxidation http://www.informaworld.com/smpp/content~content=a913927888~db=all~jumptype=rss Yoo, H. H. Kim, D. -H. In, M. K. Jin, C. Kang, M. J. Lee, S. K. 39 9 680 686 Utility of unbound plasma drug levels and P-glycoprotein transport data in prediction of central nervous system exposure http://www.informaworld.com/smpp/content~content=a913867597~db=all~jumptype=rss He, H. Lyons, K. A. Shen, X. Yao, Z. Bleasby, K. Chan, G. Hafey, M. Li, X. Xu, S. Salituro, G. M. Cohen, L. H. Tang, W. 39 9 687 693 Effect of continuous silymarin administration on oral talinolol pharmacokinetics in healthy volunteers http://www.informaworld.com/smpp/content~content=a913927873~db=all~jumptype=rss Zhou, H. -H. Tan, Z. -R. Chen, Y. Guo, D. Han, Y. 39 9 694 699 Disposition of GDC-0879, a B-RAF kinase inhibitor in preclinical species http://www.informaworld.com/smpp/content~content=a913927151~db=all~jumptype=rss Ran, Y. Wong, S. Shin, Y. Randolph, N. Plise, E. Liederer, B. Feng, J. Driscoll, J. P. Choo, E. F. 39 9 700 709 Professor George Gordon Gibson (1949-2008) http://www.informaworld.com/smpp/content~content=a913652925~db=all~jumptype=rss 39 8 557 557 A letter to Gordon http://www.informaworld.com/smpp/content~content=a913644975~db=all~jumptype=rss Estabrook, Ronald W. 39 8 558 564 Mechanism-based bioanalysis and biomarkers for hepatic chemical stress http://www.informaworld.com/smpp/content~content=a913235472~db=all~jumptype=rss Antoine, D. J. Mercer, A. E. Williams, D. P. Park, B. K. 39 8 565 577 Cynomolgus monkey CYPs: a comparison with human CYPs http://www.informaworld.com/smpp/content~content=a913646279~db=all~jumptype=rss Iwasaki, K. Uno, Y. 39 8 578 581 Species differences in the hepatic effects of inducers of CYP2B and CYP4A subfamily forms: relationship to rodent liver tumour formation http://www.informaworld.com/smpp/content~content=a913269253~db=all~jumptype=rss Lake, B. G. 39 8 582 596 Nuclear receptors: the controlling force in drug metabolism of the liver? http://www.informaworld.com/smpp/content~content=a913654796~db=all~jumptype=rss Plant, N. Aouabdi, S. 39 8 597 605 CYP1B1 , a developmental gene with a potential role in glaucoma therapy http://www.informaworld.com/smpp/content~content=a913239643~db=all~jumptype=rss Choudhary, D. Jansson, I. Schenkman, J. B. 39 8 606 615 Cell death pathways - potential therapeutic targets http://www.informaworld.com/smpp/content~content=a913233797~db=all~jumptype=rss MacFarlane, M. 39 8 616 624 Human P450s involved in drug metabolism and the use of structural modelling for understanding substrate selectivity and binding affinity http://www.informaworld.com/smpp/content~content=a913234906~db=all~jumptype=rss Lewis, D. F. V. Ito, Y. 39 8 625 635 Prediction of animal clearance using naïve Bayesian classification and extended connectivity fingerprints http://www.informaworld.com/smpp/content~content=a912550740~db=all~jumptype=rss McIntyre, T. A. Han, C. Davis, C. B. 39 7 487 494 Membrane integration of recombinant human P450 forms http://www.informaworld.com/smpp/content~content=a912498812~db=all~jumptype=rss Shukla, A. Huang, W. Depaz, I. M. Gillam, E. M. J. 39 7 495 507 Effect of sodium tanshinone II A sulfonate on the activity of CYP1A2 in healthy volunteers http://www.informaworld.com/smpp/content~content=a912500143~db=all~jumptype=rss Fan, L. Zhou, H. -H. Chen, Y. Tu, J. -H. He, Y. -J. Zhang, W. Wang, G. Tan, Z. -R. Zhou, G. 39 7 508 513 Application of multivariate statistical procedures to identify transcription factors that correlate with MRP2, 3, and 4 mRNA in adult human livers http://www.informaworld.com/smpp/content~content=a912550829~db=all~jumptype=rss Aleksunes, L. M. Yeager, R. L. Klaassen, C. D. 39 7 514 522 Predictability of intranasal pharmacokinetics in man using pre-clinical pharmacokinetic data with a dopamine 3 receptor agonist, PF-219061 http://www.informaworld.com/smpp/content~content=a912563280~db=all~jumptype=rss Huyghe, I. Verrier, H. Phipps, J. Heatherington, A. C. Attkins, N. J. 39 7 523 533 Species differences in the multiple-dose pharmacokinetics of the non-nucleoside reverse transcriptase inhibitor (NNRTI) UK-453,061 in animals and man: implications for safety considerations http://www.informaworld.com/smpp/content~content=a912498755~db=all~jumptype=rss Walker, D. K. Davis, J. Houle, C. Gardner, I. B. Webster, R. 39 7 534 543 Studies on the pharmacokinetics and metabolism of a γ-secretase inhibitor BMS-299897, and exploratory investigation of CYP enzyme induction http://www.informaworld.com/smpp/content~content=a912501204~db=all~jumptype=rss Boulton, D. W. Hansel, S. B. Felsenstein, K. M. Anderson, J. J. Barten, D. M. Pursley, J. M. Zheng, M. Wang, J. Thakur, A. Santone, K. S. Yao, M. Krishna, R. Flint, O. P. Lubinski, J. 39 7 544 555 Cocktail-substrate assay system for mechanism-based inhibition of CYP2C9, CYP2D6, and CYP3A using human liver microsomes at an early stage of drug development http://www.informaworld.com/smpp/content~content=a911822082~db=all~jumptype=rss Tsuda-Tsukimoto, M. Mori, K. Hashimoto, H. Takatsu, H. Kume, T. 39 6 415 422 Tissue distribution of CYP3A29 mRNA expression in Bama miniature pig by quantitative reverse transcriptase-polymerase chain reaction (RT-PCR) http://www.informaworld.com/smpp/content~content=a911829273~db=all~jumptype=rss Wei, H. Liu, Y. Yang, J. Shang, H. 39 6 423 429 Method for predicting the risk of drug-drug interactions involving inhibition of intestinal CYP3A4 and P-glycoprotein http://www.informaworld.com/smpp/content~content=a911822072~db=all~jumptype=rss Tachibana, T. Kato, M. Watanabe, T. Mitsui, T. Sugiyama, Y. 39 6 430 443 In vitro metabolism of the specific endothelin-A receptor antagonist ZD4054 and clinical drug interactions between ZD4054 and rifampicin or itraconazole in healthy male volunteers http://www.informaworld.com/smpp/content~content=a911822087~db=all~jumptype=rss Taboada, M. T. Swaisland, H. C. Oliver, S. D. Morris, T. Jones, H. K. Millar, A. Hargreaves, J. A. Slamon, D. McCormick, A. D. Mackey, A. Bakhtyari, A. 39 6 444 456 Pharmacokinetics of 20( S )-25-methoxyl-dammarane-3β, 12β, 20-triol and its active metabolite after oral and intravenous administration in rat http://www.informaworld.com/smpp/content~content=a911822075~db=all~jumptype=rss Xu, J. Zhao, Y. Zhang, D. Gu, J. Zhang, X. 39 6 457 464 Pharmacokinetics and first-pass effects of liquiritigenin in rats: low bioavailability is primarily due to extensive gastrointestinal first-pass effect http://www.informaworld.com/smpp/content~content=a911822085~db=all~jumptype=rss Kang, H. E. Cho, Y. K. Jung, H. Y. Choi, K. Y. Sohn, S. I. Baek, S. R. Lee, M. G. 39 6 465 475 Pharmacokinetic studies of enantiomers of ibuprofen and its chiral metabolites in humans with different variants of genes coding CYP2C8 and CYP2C9 isoenzymes http://www.informaworld.com/smpp/content~content=a911825774~db=all~jumptype=rss Główka, F. łuczak, M. Karaźniewicz-łada, M. 39 6 476 485 Influence of carboxylesterase 2 genetic polymorphisms on mycophenolic acid pharmacokinetics in Japanese renal transplant recipients http://www.informaworld.com/smpp/content~content=a910248524~db=all~jumptype=rss Satoh, S. Habuchi, T. Miura, M. Inoue, K. Suzuki, T. Saito, M. Fujiyama, N. Kagaya, H. 39 5 407 414 Variation in glucuronidation of lamotrigine in human liver microsomes http://www.informaworld.com/smpp/content~content=a910647470~db=all~jumptype=rss Remmel, R. P. Argikar, U. A. 39 5 355 363 In vitro stability and metabolism of salvinorin A in rat plasma http://www.informaworld.com/smpp/content~content=a910248482~db=all~jumptype=rss Tsujikawa, K. Kuwayama, K. Miyaguchi, H. Kanamori, T. Inoue, H. Iwata, Y. T. 39 5 391 398 Dialkyl phosphates in meconium as a biomarker of prenatal exposure to organophosphate pesticides: A study on pregnant women of rural areas in Crete, Greece http://www.informaworld.com/smpp/content~content=a910649719~db=all~jumptype=rss Sifakis, S. Toutoudaki, M. Koutroulakis, D. Tzatzarakis, M. N. Tsatsakis, A. M. 39 5 364 373 Assessment of cryopreserved human hepatocytes as a model system to investigate sulfation and glucuronidation and to evaluate inhibitors of drug conjugation http://www.informaworld.com/smpp/content~content=a910251501~db=all~jumptype=rss Coughtrie, M. Nolan, A. Patel, A. Bloomer, J. Riches, Z. 39 5 374 381 Hydroxylation of tanshinone IIa in human liver microsomes is specifically catalysed by cytochrome P4502A6 http://www.informaworld.com/smpp/content~content=a910647982~db=all~jumptype=rss Li, W. He, Y. -Q. Liu, Y. Hu, Y. Liu, H. -X. Yang, L. 39 5 382 390 Role of human CYP1A1 and NAT2 in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced mutagenicity and DNA adducts http://www.informaworld.com/smpp/content~content=a910647839~db=all~jumptype=rss States, J. C. Smith, N. B. Neale, J. R. Holloman, J. L. Pierce Jr, W. M Hein, D. W. Jiang, G. Doll, M. A. Metry, K. J. Bendaly, J. 39 5 399 406 Mechanism-based inhibition of CYP1A2 by antofloxacin, an 8-NH 2 derivative of levofloxacin in rats http://www.informaworld.com/smpp/content~content=a909819825~db=all~jumptype=rss Liu, X. D. Wang, G. J. Xie, L. Liao, J. Zhu, Q. 39 4 293 301