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Xenobiotica
The fate and safety evaluation of foreign compounds in biological systems
, Volume
38
Issue 7 & 8 2008
Xenobiotic and Endobiotic Transporters: Structure, Function and Regulation
ISSN:
1366-5928 (electronic) 0049-8254 (paper)
Publication Frequency:
12 issues per year
Subjects:
Pharmacology
;
Toxicology
;
Publisher:
Informa Healthcare
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Obituary
Professor George Gordon Gibson BSc, PhD, DSc, FRCPath, FBTS 1949–2008
Nick Plant
Page 653
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Editorial
Editorial overview
Nick Plant; Curtis D. Klaassen
Pages 654 – 655
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Original Articles
Determination and modelling of stereoselective interactions of ligands with drug transporters: A key dimension in the understanding of drug disposition
P. Bhatia; M. Kolinski; R. Moaddel; K. Jozwiak; I. W. Wainer
Pages 656 – 675
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Role of transport proteins in drug discovery and development: a pharmaceutical perspective
A. Ayrton; P. Morgan
Pages 676 – 708
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A regulatory viewpoint on transporter-based drug interactions
L. Zhang; Y. (D.) Zhang; J. M. Strong; K. S. Reynolds; S. -M. Huang
Pages 709 – 724
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Nuclear hormone receptor-dependent regulation of hepatic transporters and their role in the adaptive response in cholestasis
S. Stahl; M. R. Davies; D. I. Cook; M. J. Graham
Pages 725 – 777
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Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family
B. Hagenbuch; C. Gui
Pages 778 – 801
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Structure, function and regulation of P-glycoprotein and its clinical relevance in drug disposition
S. -F. Zhou
Pages 802 – 832
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MRP class of human ATP binding cassette (ABC) transporters: historical background and new research directions
Y. Toyoda; Y. Hagiya; T. Adachi; K. Hoshijima; M. T. Kuo; T. Ishikawa
Pages 833 – 862
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Human ABC transporters ABCG2 (BCRP) and ABCG4
S. Koshiba; R. An; H. Saito; K. Wakabayashi; A. Tamura; T. Ishikawa
Pages 863 – 888
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Physiology, structure, and regulation of the cloned organic anion transporters
C. Srimaroeng; J. L. Perry; J. B. Pritchard
Pages 889 – 935
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Organic cation transporters
G. Ciarimboli
Pages 936 – 971
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SLC28 genes and concentrative nucleoside transporter (CNT) proteins
M. Pastor-Anglada; P. Cano-soldado; E. Errasti-murugarren; F. J. Casado
Pages 972 – 994
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Human equilibrative nucleoside transporter (ENT) family of nucleoside and nucleobase transporter proteins
J. D. Young; S. Y. M. Yao; L. Sun; C. E. Cass; S. A. Baldwin
Pages 995 – 1021
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Peptide transporters and their roles in physiological processes and drug disposition
I. Rubio-Aliaga; H. Daniel
Pages 1022 – 1042
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Bile acid transporters in health and disease
A. Kosters; S. J. Karpen
Pages 1043 – 1071
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The SLC16 monocaboxylate transporter family
D. Meredith; H. C. Christian
Pages 1072 – 1106
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Multidrug and toxic compound extrusion (MATE)-type proteins as anchor transporters for the excretion of metabolic waste products and xenobiotics
Y. Moriyama; M. Hiasa; T. Matsumoto; H. Omote
Pages 1107 – 1118
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Cholesterol and non-cholesterol sterol transporters: ABCG5, ABCG8 and NPC1L1: a review
S. Kidambi; S. B. Patel
Pages 1119 – 1139
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Validation and application of Caco-2 assays for the
in vitro
evaluation of development candidate drugs as substrates or inhibitors of P-glycoprotein to support regulatory submissions
R. Elsby; D. D. Surry; V. N. Smith; A. J. Gray
Pages 1140 – 1164
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