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Xenobiotica The fate and safety evaluation of foreign compounds in biological systems, Volume 38 Issue 2 2008

Xenobiotica is moving!

ISSN: 1366-5928 (electronic) 0049-8254 (paper)
Publication Frequency: 12 issues per year
Subjects: Pharmacology; Toxicology;
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Original Articles
Ketoconazole and the modulation of multidrug resistance-mediated transport in Caco-2 and MDCKII-MDR1 drug transport models
Y. Fan; R. Rodriguez-Proteau
Pages 107 – 129
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Molecular modelling study of the mechanism of high-potency inhibition of human catechol-O-methyltransferase by (–)-epigallocatechin-3-O-gallate
B. T. Zhu;  J. -Y. Shim;  M. Nagai; H. -W. Bai
Pages 130 – 146
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Effects of dietary salt on the expression of drug transporters, cytochrome P4503a, and nuclear receptors in rats
H. J. Kang;  I. S. Song;  S. S. Lee;  M. A. Yoo; J. G. Shin
Pages 147 – 155
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Metabolism of OR-1896, a metabolite of levosimendan, in rats and humans
M. Koskinen;  J. Puttonen;  M. Pykäläinen;  A. Vuorela; T. Lotta
Pages 156 – 170
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Metabolism and disposition of [14C]5-amino-o-cresol in female F344 rats and B6C3F1 mice
B. Hedtke;  Z. Gao;  L. -J. Chen;  W. M. Weber; K. J. Dix
Pages 171 – 184
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Preclinical factors affecting the pharmacokinetic behaviour of tanshinone IIA, an investigational new drug isolated from Salvia miltiorrhiza for the treatment of ischaemic heart diseases
H. -C. Bi;  Z. Zuo;  X. Chen;  C. -S. Xu;  Y. -Y. Wen;  H. -Y. Sun;  L. -Z. Zhao;  Y. Pan;  Y. Deng;  P. -Q. Liu;  L. -Q. Gu;  Z. -Y. Huang;  S. -F. Zhou; M. Huang
Pages 185 – 222
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Importance of mechanistic drug metabolism studies in support of drug discovery: A case study with an N -sulfonylated dipeptide VLA-4 antagonist in rats
W. Tang;  R. A. Stearns;  Q. Chen;  K. Bleasby;  Y. Teffera;  A. Colletti;  M. Hafey;  R. Evers;  D. C. Dean;  P. A. Magriotis;  T. J. Lanza;  L. S. Lin;  W. K. Hagmann; T. A. Baillie
Pages 223 – 237
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