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Amyotrophic Lateral Sclerosis, Volume 9 Issue 1 2008

Amyotrophic Lateral Sclerosis is moving!
The official publication of the World Federation of Neurology Research Group on Motor Neuron Disease
2008 Impact Factor: 1.815 (ISI Web of Knowledge, 2008 Journal Citation Reports)
ISSN: 1471-180X (electronic) 1748-2968 (paper)
Publication Frequency: 6 issues per year
Subject: Neurology;
Previously published as: Amyotrophic Lateral Sclerosis and other Neuron Disorders (1466-0822, 1471-180X) until 2006
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Editorial
A new editor for the “Black but not bleak” journal – ALS research is coming of age
Page 3
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Review Article
Design, power, and interpretation of studies in the standard murine model of ALS
Sean Scott;  Janice E. Kranz;  Jeff Cole;  John M. Lincecum;  Kenneth Thompson;  Nancy Kelly;  Alan Bostrom;  Jill Theodoss;  Bashar M. Al-Nakhala;  Fernando G. Vieira;  Jeyanthi Ramasubbu; James A. Heywood
Pages 4 – 15
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Original Articles
Design of phase II ALS clinical trials
David A. Schoenfeld; Merit Cudkowicz
Pages 16 – 23
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Neuromuscular dysfunction in the mutant superoxide dismutase mouse model of amyotrophic lateral sclerosis
Wade S. Parkhouse;  Lori Cunningham;  Ingrid McFee;  Jennifer M. Litt Miller;  Darryl Whitney;  Steven L. Pelech; Charles Krieger
Pages 24 – 34
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The rare G93D mutation causes a slowly progressing lower motor neuron disease
Gabriella Restagno;  Federica Lombardo;  Luca Sbaiz;  Cristina Mari;  Cinzia Gellera;  Dario Alimonti;  Andrea Calvo;  Luisella Tarenzi; Adriano Chiò
Pages 35 – 39
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Pure bulbar motor neuron involvement linked to an abnormal CAG repeat expansion in the androgen receptor gene
Julien Praline;  Anne-Marie Guennoc;  Marie-Claire Malinge;  Bertrand de Toffol; Philippe Corcia
Pages 40 – 42
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Neuronal loss associated with cognitive performance in amyotrophic lateral sclerosis: An (11C)-flumazenil PET study
Paul Wicks;  Martin R. Turner;  Sharon Abrahams;  Alexander Hammers;  David J. Brooks;  P. Nigel Leigh; Laura H. Goldstein
Pages 43 – 49
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R(+) pramipexole as a mitochondrially focused neuroprotectant: Initial early phase studies in ALS
Hua Wang;  Kylyana S. Larriviere;  Kristen E. Keller;  Kathleen A. Ware;  Ted M. Burns;  Mark A. Conaway;  David Lacomis;  Gary L. Pattee;  Lawrence H. Phillips II;  Nina J. Solenski;  Sasa A. Zivkovic; James P. Bennett Jr
Pages 50 – 58
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Causes of death in a post-mortem series of ALS patients
Philippe Corcia;  Pierre-François Pradat;  François Salachas;  Gaëlle Bruneteau;  Nadine le Forestier;  Danielle Seilhean;  Jean-Jacques Hauw; Vincent Meininger
Pages 59 – 62
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Errata
Erratum
Page 63
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