Minority populations in the United States continue to experience a disproportionate share of emergency department (ED) visits and hospitalizations due to asthma. This review examines programs that have attempted to reduce these acute care visits in African American and Hispanic patients. We performed a PubMed search of the English literature for studies published from March 1990 to March 2005, aimed at reducing ED visits and hospitalizations in patients with asthma. Decreased acute care visits in African American and Hispanic patients with asthma have been demonstrated in several studies over the past 15 years, including collaboration by physicians, nurses, and clinical pharmacists in achieving this goal. These studies have shown that reduced acute care visits are associated with optimal drug therapy per national guidelines, concurrent with patient education, environmental control, and objective monitoring of this inflammatory airway disease. Early intensive patient education was a key feature of these successful programs. Written action plans, including early use of oral corticosteroids at home, and rapport with patients are other key components of programs that have resulted in a decrease in ED visits and hospitalizations.