Ring-Closing Metathesis Strategies to P -heterocycles
Authors:
Kevin T. Sprott a;
Matthew D. McReynolds a;
Paul R. Hanson a
| Affiliation: | a Department of Chemistry, University of Kansas, Lawrence, KS. |
DOI:
10.1080/10426500212282
Publication Frequency:
12 issues per year
Published in:
Phosphorus, Sulfur, and Silicon and the Related Elements,
Volume
177,
Issue
6 &
7
June
2002
, pages 1807
- 1809
Formats available:
PDF
(English)
View Article:
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Abstract
A general approach to the synthesis of P -heterocycles using the ring-closing metathesis reaction is described. We have developed a new method utilizing phosphorus nuclei as suitable temporary tethers for the coupling of non-racemic allylic amines. This approach allows for the generation of symmetric and unsymmetric 1,4-diamines. Subsequent coupling of these 1,4-diamines with various nuclei produces an array of 7-membered heterocycles.
|
| Keywords: 1,4-Diamine; P -heterocycle; Ring-closing Metathesis Cyclic Phosphonamide; Temporary Phosphorus Tether |

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