New automated instrumentation for the rapid acquisition of aerosol sampler aspiration efficiency data has been applied to an investigation of a range of personal aerosol samplers of the type developed during the 1980s at the Institute of Occupational Medicine (IOM) in Edinburgh, Scotland, U.K. The experimental research was carried out in a small wind tunnel, and the relation of the results for IOM-like samplers to full-scale life-size personal aerosol sampling scenarios—like those encountered in occupational aerosol exposure assessment—was investigated by reference to the scaling laws that have been developed based on familiar aerosol mechanics as they apply to the physics of aerosol sampling. In the small-scale experimental study, the IOM-like sampler was mounted centrally on a rectangular bluff body, simulating the wearing of the sampler on the body (e.g., as by a worker in an industrial setting). Scaling with respect to the corresponding, more-realistic full-scale system for a corresponding full-scale windspeed of 1.0 m/s was achieved by varying the inlet diameter, the windspeed and the sampling flowrate. The results for windspeeds in the scaled experiments of 1.5 m/s and lower were found to differ significantly from those for windspeeds of 2.0 m/s and higher. In particular, the measured aspiration efficiency values for the lower windspeeds were markedly higher than—and clearly not consistent with—the higher windspeed group of results. It is considered likely that such divergence may be associated with a characteristic of the small wind tunnel in which the experiments were conducted. However, the scaling laws developed were found to work well for windspeeds in the scaled experiments of 1.5 m/s and higher. The results confirm that the performance of the IOM personal inhalable aerosol sampler is in quite good general agreement with the inhalability criterion.