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Acute nitrate poisoning in two cattle 

Authors: Mustafa Issi a;  Yusuf Gul a;  Ahmet Atessahin a; Izzet Karahan a
Affiliation:   a Faculty of Veterinary Medicine, Department of Pharmacology and Toxicology, University of Firat, 23119 Elazig, Turkey
DOI: 10.1080/02772240701365649
Publication Frequency: 8 issues per year
Published in: journal Toxicological & Environmental Chemistry, Volume 90, Issue 1 January 2008 , pages 135 - 140
First Published: January 2008
Formats available: HTML (English) : PDF (English)
Previously published as: Toxicological & Environmental Chemistry Reviews (0092-9867) until 1980
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Abstract

This article reports on a nitrate poisoning case in two cattle [a Montafon cross cow at 4 years age (Protocol no 571) and a Simmental cross heifer at 1.5 year age (Protocol no 572)] with suspected acute nitrate poisoning which were brought to the clinic of the Department of Internal Disease, Faculty of Veterinary Medicine, Fırat University. The animals were reported to consume feed mixed with ammonium nitrate fertilizer. According to anamnesis, clinical inspection and laboratory analyses, an acute nitrate poisoning was established in both animals. Immediately after diagnosis, a dose of 20 mg kg-1 methylene blue was administered intravenously to decrease methaemoglobinaemia developed after poisoning. Various parameters determined by clinical examinations and laboratory analysis after treatment were observed to return normal values. It is concluded that using methylene blue alone can cure acute nitrate poisoning in cattle.
Keywords: Nitrate-nitrite poisoning; cow; methylene blue; methaemoglobin
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