The purpose of this article is to employ the dynamic translog framework to model inter-factor and inter-fuel energy demand for the Thai manufacturing sector. The Denny et al. (1981) and Lynk (1989) framework, which proposes a dynamic adjustment for capital stock is employed to motivate the estimated of factor demand and fuel share equations. Three factors: energy, labour and capital; and five fuel types: fuel oil, diesel oil, liquified petroleum gas (LPG), electricity, and coal and lignite; are examined. Regression diagnostics support the empirical specification. Numerous factor and fuel substitution possibilities are identified, with some policy implications described.