Refugees are a particularly vulnerable population that is at risk for mental health problems for a variety of reasons: traumatic experiences in and escapes from their countries of origin, difficult camp or transit experiences, culture conflict and adjustment problems in the country of resettlement, and multiple losses—family members, country, and way of life. Afghan refugees comprise the largest refugee population in the world, at its peak numbering more than 6 million, living mainly in Pakistan and Iran. Based on an ethnographic study of Afghan refugees in Northern California, this article describes common antecedents to and examples of mental health problems in this population, such as depression, somatic symptoms, and posttraumatic stress disorder. It reviews some of the literature on traumatized refugees and makes some suggestions to mental health providers.