High incidences of slope movement are observed throughout Cuyahoga River watershed in northeast Ohio, USA. The major type of slope failure involves rotational movement in steep stream walls where erosion of the banks creates over-steepened slopes. The occurrence of landslides in the area depends on a complex interaction of natural as well as human induced factors, including: rock and soil strength, slope geometry, permeability, precipitation, presence of old landslides, proximity to streams and flood-prone areas, land use patterns, excavation of lower slopes and/or increasing the load on upper slopes, alteration of surface and subsurface drainage. These factors were used to evaluate the landslide-induced hazard in Cuyahoga River watershed using logistic regression analysis, and a landslide susceptibility map was produced in ArcGIS. The map classified land into four categories of landslide susceptibility: low, moderate, high, and very high. The susceptibility map was validated using known landslide locations within the watershed area. The landslide susceptibility map produced by the logistic regression model can be efficiently used to monitor potential landslide-related problems, and, in turn, can help to reduce hazards associated with landslides.