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An Inexpensive Autosampler to Maximize Throughput for an Ion Source that Samples Surfaces in Open Air 

Author: Andrew H. Grange a
Affiliation:   a United States Environmental Protection Agency, Office of Research and Development, National Research Laboratory, Environmental Sciences Division, USA
DOI: 10.1080/15275920802115860
Publication Frequency: 4 issues per year
Published in: journal Environmental Forensics, Volume 9, Issue 2 & 3 April 2008 , pages 127 - 136
First Published on: 01 April 2008
Formats available: HTML (English) : PDF (English)
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Abstract

Rapid analysis of hundreds of wipe samples after a chemical dispersion event is essential for quickly characterizing the hazard posed to the public. An autosampler was built to pull 76 cotton swabs mounted along a 91-cm (3-foot) long, square aluminum rod in open air, through the ionizing beam of a direct analysis in real time (DART1) ion source interfaced to a time-of-flight mass spectrometer. The rod and swabs mounted on N-scale model railroad flat cars were pulled through the ion source in 7.5 min by a 7-rpm motor. Percent relative standard deviations (%RSDs) of 18.5% to 21.3% were obtained for the chromatographic peak areas of the protonated molecule. Maximum-to-minimum ratios of the areas were between 2.22 and 2.71. Measured exact masses of analyte ions were always accurate to within 1 mDa.
Keywords: homeland security; autosampler; DART; throughput; time-of-flight mass spectrometer
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