Multiple steady state profiles in interconnected biological systems
Authors:
A. K. Dram
a;
J. Harmand b;
A. Rapaport a;
C. Lobry c
a;
J. Harmand b;
A. Rapaport a;
C. Lobry c
| Affiliations: | a UMR Analyse des Syst mes et Biom trie, INRA, Montpellier, France |
| b Lab. de Biotechnologie de l'Environnement, INRA, Narbonne, France | |
| c INRIA Sophia-Antipolis, Sophia-Antipolis |
DOI:
10.1080/13873950600723277
Publication Frequency:
6 issues per year
Published in:
Mathematical and Computer Modelling of Dynamical Systems,
Volume
12,
Issue
5
October
2006
, pages 379
- 393
Subjects:
Analysis - Mathematics;
Applied Mechanics;
Dynamical Control Systems;
Dynamical Systems;
Mathematical Modelling;
Mathematics & Statistics for Engineers;
Simulation & Modeling;
Formats available:
HTML
(English)
:
PDF
(English)
Previously published as:
Mathematical Modelling of Systems
(1381-2424)
until 1998
View Article:
View Article (PDF)
View Article (HTML)
Abstract
This paper deals with a generic approach for the analysis of interconnected biological systems. The equilibrium points as well as the asymptotic behaviour of these systems are investigated from a qualitative point of view. In particular, a new generic approach is used to show that a series of Continuously Stirred Tank Reactors (CSTRs) can exhibit multiple steady state profiles, for any non-monotonic kinetics. This multiplicity property disappears when the number of reactors becomes sufficiently large (for a given total volume). These results are to be taken in account when CSTRs in series are used to approximate a Piston Flow Reactor (PFR).
|
| Keywords: Biological systems; Multiple steady states; Interconnected systems; Convergence; Substrate inhibited kinetics |
| view references (12) |

Download Citation


mes et Biom
CiteULike
Del.icio.us
BibSonomy
Connotea