Synthesis of N-Methyl Secondary Amines

Authors: Hephzibah J. Kumpaty ^a; John S. Williamson ^b; Sukanta Bhattacharyya ^c

Affiliations:	^a Department of Chemistry, University of Wisconsin-Whitewater, Wisconsin, USA
	^b Department of Medicinal Chemistry, School of Pharmacy, The University of Mississippi, Mississippi, USA
	^c Argonaut Technologies, Foster City, California, USA

DOI: 10.1081/SCC-120018703

Publication Frequency: 24 issues per year

Published in: journal

Synthetic Communications, Volume 33, Issue 8 January 2003 , pages 1411 - 1416

Subject: Organic Chemistry;

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Abstract

A diverse set of N-methyl secondary amines are obtained in high yields by an expedient reductive alkylation of commercially available methanolic methylamine.

Keywords: Reductive alkylation; Methylamine; Titanium(IV) isopropoxide; Sodium borohydride

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Synthesis of N-Methyl Secondary Amines

Abstract