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Saccharomyces boulardii induced sepsis: Successful therapy with voriconazole after treatment failure with fluconazole 

Authors: Olaf Burkhardt a;  Thomas Koumlhnlein b;  Mathias W. Pletz c; Tobias Welte ab
Affiliations:   a From the Department of Pulmonary and Critical Care Medicine, University Otto-von-Guericke, Magdeburg, Germany
b Department for Pulmonary Medicine, Medical School Hannover, Germany
c Department of International Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA
DOI: 10.1080/00365540510026454
Publication Frequency: 10 issues per year
Published in: journal Scandinavian Journal of Infectious Diseases, Volume 37, Issue 1 January 2005 , pages 69 - 72
Number of References: 41
Formats available: HTML (English) : PDF (English)
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Abstract

Saccharomyces boulardii is frequently used for prevention and treatment of all forms of diarrhoea. We report the case of a 19-y-old white male with an underlying severe neurological disease, who developed a fungal sepsis after prophylactic application of a drug containing S. boulardii. Initial treatment with fluconazole was not successful. After the application of voriconazole, the sepsis resolved completely. This is the first clinical report of a successful treatment of Saccharomyces sepsis with voriconazole.
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