Saccharomyces boulardii induced sepsis: Successful therapy with voriconazole after treatment failure with fluconazole
Authors:
Olaf Burkhardt a;
Thomas K
hnlein b;
Mathias W. Pletz c;
Tobias Welte ab
hnlein b;
Mathias W. Pletz c;
Tobias Welte ab
| Affiliations: | a From the Department of Pulmonary and Critical Care Medicine, University Otto-von-Guericke, Magdeburg, Germany |
| b Department for Pulmonary Medicine, Medical School Hannover, Germany | |
| c Department of International Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA |
DOI:
10.1080/00365540510026454
Publication Frequency:
10 issues per year
Published in:
Scandinavian Journal of Infectious Diseases,
Volume
37,
Issue
1
January
2005
, pages 69
- 72
Subject:
Infectious Diseases;
Number of References: 41
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Abstract
Saccharomyces boulardii is frequently used for prevention and treatment of all forms of diarrhoea. We report the case of a 19-y-old white male with an underlying severe neurological disease, who developed a fungal sepsis after prophylactic application of a drug containing S. boulardii. Initial treatment with fluconazole was not successful. After the application of voriconazole, the sepsis resolved completely. This is the first clinical report of a successful treatment of Saccharomyces sepsis with voriconazole.
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