The Ca' Lita landslide is a large and deep-seated mass movement located in the northern Apennines, about 70 km west of Bologna (Northern Italy). It consists of a composite landslide that affects Cretaceous to Eocene flysch rock masses and chaotic complexes. Many of the sectors making up the landslide have resumed activity between 2002 and 2006, threatening some villages and an important road connecting several key industrial facilities located in the upper watershed. This paper presents the management of the emergency, dealing with the investigation campaigns (geological, geomorphological and LiDAR surveys, borehole drillings, seismic surveys), with the monitoring (in situ instrumentation) and with the design and construction of mitigation measures. The whole process, from landslide reactivation to date, has been modelled on a numerical basis with the finite difference code FLAC 2D, to assess the efficiency of the mitigation system and to propose further countermeasure works in different scenarios.