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Xenobiotica
The fate and safety evaluation of foreign compounds in biological systems
, Volume
37
Issue 2 2007
ISSN:
1366-5928 (electronic) 0049-8254 (paper)
Publication Frequency:
12 issues per year
Subjects:
Pharmacology
;
Toxicology
;
Publisher:
Informa Healthcare
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Original Articles
Effect of valerian, valerian/hops extracts, and valerenic acid on glucuronidation
in vitro
K. M. Alkharfy; R. F. Frye
Pages 113 – 123
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Attenuating pregnane X receptor (PXR) activation: A molecular modelling approach
Y. -D. Gao; S. H. Olson; J. M. Balkovec; Y. Zhu; I. Royo; J. Yabut; R. Evers; E. Y. Tan; W. Tang; D. P. Hartley; R. T. Mosley
Pages 124 – 138
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Drug–drug interactions in the metabolism of imidafenacin: Role of the human cytochrome P450 enzymes and UDP-glucuronic acid transferases, and potential of imidafenacin to inhibit human cytochrome P450 enzymes
N. Kanayama; C. Kanari; Y. Masuda; S. Ohmori; T. Ooie
Pages 139 – 154
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Comparative modelling of the human UDP-glucuronosyltransferases: Insights into structure and mechanism
C. W. Locuson; T. S. Tracy
Pages 155 – 168
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Identification of human cytochrome P450 enzymes involved in the major metabolic pathway of fluvoxamine
M. Miura; T. Ohkubo
Pages 169 – 179
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Induction of cytochrome P450 enzymes in rat liver by two conazoles, myclobutanil and triadimefon
G. Sun; R. D. Grindstaff; S. -F. Thai; G. R. Lambert; D. B. Tully; D. J. Dix; S. Nesnow
Pages 180 – 193
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Metabolism of (
-
)-fenchone by CYP2A6 and CYP2B6 in human liver microsomes
M. Miyazawa; K. Gyoubu
Pages 194 – 204
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Characterization of benzimidazole and other oxidative and conjugative metabolites of brimonidine
in vitro
and in rats
in vivo
using on-line H/D exchange LC-MS/MS and stable-isotope tracer techniques
J. Ni; J. Rowe; T. Heidelbaugh; S. Sinha; A. Acheampong
Pages 205 – 220
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