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Xenobiotica The fate and safety evaluation of foreign compounds in biological systems, Volume 37 Issue 5 2007

Xenobiotica is moving!

ISSN: 1366-5928 (electronic) 0049-8254 (paper)
Publication Frequency: 12 issues per year
Subjects: Pharmacology; Toxicology;
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Original Articles
Cytochrome P450 probe substrate metabolism kinetics in Sprague Dawley rats
J. P. Chovan;  S. C. Ring;  E. Yu; J. P. Baldino
Pages 459 – 473
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Gemfibrozil and its glucuronide inhibit the hepatic uptake of pravastatin mediated by OATP1B1
R. Nakagomi-Hagihara;  D. Nakai;  T. Tokui;  T. Abe; T. Ikeda
Pages 474 – 486
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Effect of enalapril on the in vitro and in vivo peptidyl cleavage of a potent VLA-4 antagonist
B. V. Karanam;  A. Jayraj;  M. Rabe;  Z. Wang;  C. Keohane;  J. Strauss; S. Vincent
Pages 487 – 502
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Plasma pharmacokinetics and CYP3A12-dependent metabolism of c-kit inhibitor imatinib in dogs
M. Ishizuka;  S. Nagai;  K. Q. Sakamoto; S. Fujita
Pages 503 – 513
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The pharmacokinetics and disposition of MK-0524, a Prostaglandin D2 receptor 1 antagonist, in rats, dogs and monkeys
S. W. Chang;  V. Reddy;  T. Pereira;  B. J. Dean;  Y.-Q. Xia;  C. Seto;  R. B. Franklin; B. V. Karanam
Pages 514 – 533
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Disposition and metabolism of (2S,3S,4R)-N′′-cyano-N-(6-amino-3,4-dihydro-3-hydroxy-2-methyl-2-dimethoxy methyl-2H-benzopyran-4-yl)-N′-benzylguanidine, a novel neuroprotective agent for ischemia-reperfusion damage, in rats
N. S. Kim;  H. H. Yoo;  M. W. Lee;  H. S. Kim; D. H. Kim
Pages 534 – 548
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Disposition of sanguinarine in the rat
R. Večeřa;  B. Klejdus;  P. Kosina;  J. Orolin;  M. Stiborová;  S. Smrček;  J. Vičar;  Z. Dvořák;  J. Ulrichová;  V. Kubáň;  P. Anzenbacher; V. Šimánek
Pages 549 – 558
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Metabolism and excretion of CP-122,721, a non-peptide antagonist of the neurokinin NK1 receptor, in dogs: Identification of the novel cleaved product 5-trifluoromethoxy salicylic acid in plasma
A. Kamel;  Y. Du;  K. Colizza; C. Prakash
Pages 559 – 578
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