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Xenobiotica The fate and safety evaluation of foreign compounds in biological systems, Volume 37 Issue 8 2007

Xenobiotica is moving!

ISSN: 1366-5928 (electronic) 0049-8254 (paper)
Publication Frequency: 12 issues per year
Subjects: Pharmacology; Toxicology;
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Original Articles
In vitro metabolism of eupatilin by multiple cytochrome P450 and UDP-glucuronosyltransferase enzymes
H. S. Lee;  H. Y. Ji;  E. J. Park; S. Y. Kim
Pages 803 – 817
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Functional involvement of organic cation transporter1 (OCT1/Oct1) in the hepatic uptake of organic cations in humans and rats
K.-I. Umehara;  T. Iwatsubo;  K. Noguchi; H. Kamimura
Pages 818 – 831
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The metabolism of the 5HT3 antagonists ondansetron, alosetron and GR87442 I: A comparison of in vitro and in vivo metabolism and in vitro enzyme kinetics in rat, dog and human hepatocytes, microsomes and recombinant human enzymes
G. I. Somers;  A. J. Harris;  M. K. Bayliss; J. B. Houston
Pages 832 – 854
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The metabolism of the 5HT3 antagonists, ondansetron, alosetron and GR87442 II: Investigation into the in vitro methods used to predict the in vivo hepatic clearance of ondansetron, alosetron and GR87442 in the rat, dog and human
G. I. Somers;  M. K. Bayliss; J. B. Houston
Pages 855 – 869
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Use of Freund's Complete Adjuvant (FCA) in inflammatory pain models: Consequences on the metabolism and pharmacokinetics of the non-peptidic delta receptor agonist SNC80 in the rat
D. Projean;  E. Lessard;  M. P. Ducharme; J. Ducharme
Pages 870 – 883
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Disposition and metabolic fate of prasugrel in mice, rats, and dogs
R. L. Smith;  T. A. Gillespie;  T. J. Rash;  A. Kurihara; N. A. Farid
Pages 884 – 901
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