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Xenobiotica The fate and safety evaluation of foreign compounds in biological systems, Volume 38 Issue 3 2008

Xenobiotica is moving!

ISSN: 1366-5928 (electronic) 0049-8254 (paper)
Publication Frequency: 12 issues per year
Subjects: Pharmacology; Toxicology;
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Original Articles
Non-invasive method to detect induction of CYP3A4 in chimeric mice with a humanized liver
C. Emoto;  Y. Yamato;  Y. Sato;  H. Ohshita;  M. Katoh;  C. Tateno;  T. Yokoi;  K. Yoshizato; K. Iwasaki
Pages 239 – 248
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Leukotriene B4 12-hydroxydehydrogenase/15-ketoprostaglandinΔ13-reductase (LTB4 12-HD/PGR) responsible for the reduction of a double-bond of the α,β-unsaturated ketone of an aryl propionic acid non-steroidal anti-inflammatory agent CS-670
K. Itoh;  K. Yamamoto;  M. Adachi;  T. Kosaka; Y. Tanaka
Pages 249 – 263
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Metabolism and related human risk factors for hepatic damage by usnic acid containing nutritional supplements
R. S. Foti;  L. J. Dickmann;  J. A. Davis;  R. J. Greene;  J. J. Hill;  M. L. Howard;  J. T. Pearson;  D. A. Rock;  J. C. Tay;  J. L. Wahlstrom; J. G. Slatter
Pages 264 – 280
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In vitro metabolism of KBH-A40, a novel δ-lactam-based histone deacetylase (HDAC) inhibitor, in human liver microsomes and serum
H. M. Kim;  S. J. Oh;  S. -K. Park;  G. Han;  K. Kim;  K. S. Lee;  J. S. Kang;  M. Nam; K. Lee
Pages 281 – 293
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In vitro metabolism and interactions of pyridostigmine bromide, N,N-diethyl-m-toluamide, and permethrin in human plasma and liver microsomal enzymes
A. W. Abu-Qare; M. B. Abou-Donia
Pages 294 – 313
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Urinary excretion of the main metabolites of 3,4-methylenedioxymethamphetamine (MDMA), including the sulfate and glucuronide of 4-hydroxy-3-methoxymethamphetamine (HMMA), in humans and rats
N. Shima;  M. Katagi;  H. Kamata;  K. Zaitsu;  T. Kamata;  M. Nishikawa;  A. Miki;  H. Tsuchihashi;  T. Sakuma; N. Nemoto
Pages 314 – 324
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Pharmacokinetics and tissue distribution of 3-((5-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)-1H-imidazol-2-yl)methyl)benzamide; a novel ALK5 inhibitor and a potential anti-fibrosis drug
Y. W. Kim;  Y. K. Kim;  J. Y. Lee;  K. T. Chang;  H. J. Lee;  D. -K. Kim; Y. Y. Sheen
Pages 325 – 339
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Preclinical absorption, distribution, metabolism and excretion (ADME) characterization of ICAM1988, an LFA-1/ICAM antagonist, and its prodrug
S. C. Khojasteh;  D. D. Leipold;  F. Lai;  H. La;  M. J. Baumgardner;  K. E. Desino;  O. S. Gudmundsson;  D. C. Bloedow;  S. C. Bodary;  M. E. Reynolds;  T. R. Gadek; S. Kenkare-Mitra
Pages 340 – 352
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