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Xenobiotica The fate and safety evaluation of foreign compounds in biological systems, Volume 38 Issue 4 2008

Xenobiotica is moving!

ISSN: 1366-5928 (electronic) 0049-8254 (paper)
Publication Frequency: 12 issues per year
Subjects: Pharmacology; Toxicology;
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General Xenobiochemistry
Prediction of metabolic clearance using fresh human hepatocytes: Comparison with cryopreserved hepatocytes and hepatic microsomes for five benzodiazepines
D. Hallifax;  A. Galetin; J. B. Houston
Pages 353 – 367
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In vivo approach for the evaluation of mechanism-based inhibition of cytochrome P450 3A in rats
N. Sekiguchi;  M. Kato;  M. Takada;  H. Watanabe;  A. Higashida;  S. Sakai;  M. Ishigai; Y. Aso
Pages 368 – 381
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Clinical Pharmacokinetics and Metabolism
Pharmacokinetic characterization of hydroxylpropyl-β-cyclodextrin-included complex of cryptotanshinone, an investigational cardiovascular drug purified from Danshen (Salvia miltiorrhiza)
Y. Pan;  H. -C. Bi;  G. -P. Zhong;  X. Chen;  Z. Zuo;  L. -Z. Zhao;  L. -Q. Gu;  P. -Q. Liu;  Z. -Y. Huang;  S. -F. Zhou; M. Huang
Pages 382 – 398
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Disposition and metabolism of the colchicine derivative [14C]-ZD6126 in rat and dog
E. A. Partridge;  R. A. D'souza;  E. M. Lenz;  S. M. Smith;  J. Clarkson-Jones; D. W. Roberts
Pages 399 – 421
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Dietary salt does not influence the disposition of verapamil enantiomers in relation to efflux transporter ABCB1 genetic polymorphism in healthy Korean subjects
W. Pan;  J. Y. Ryu;  J. H. Shon;  I. S. Song;  K. H. Liu;  Y. E. Sunwoo;  W. Kang; J. G. Shin
Pages 422 – 434
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Molecular Toxicology
Effect of gender, dose, and time on 3-(3,5-dichlorophenyl)-2,4-thiazolidinedione (DCPT)-induced hepatotoxicity in Fischer 344 rats
N. N. Patel;  C. M. Crincoli;  E. L. Kennedy;  D. M. Frederick;  R. Tchao; P. J. Harvison
Pages 435 – 449
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