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Xenobiotica The fate and safety evaluation of foreign compounds in biological systems, Volume 38 Issue 5 2008

ISSN: 1366-5928 (electronic) 0049-8254 (paper)

Publication Frequency: 12 issues per year

Subjects: Pharmacology; Toxicology;

Publisher: Informa Healthcare

Issue Purchase: No online purchase options available.

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General Xenobiochemistry
	Identification of human cytochrome P450 enzymes involved in the metabolism of IN-1130, a novel activin receptor-like kinase-5 (ALK5) inhibitor Y. W. Kim; Y. K. Kim; D. -K. Kim; Y. Y. Sheen Pages 451 – 464 Abstract \| References \| Full Text PDF \| Full Text HTML \| Request Permissions Related Articles	buy now
	Induction of cytochrome P450s by terpene trilactones and flavonoids of the Ginkgo biloba extract EGb 761 in rats Y. Deng; H. -C. Bi; L. -Z. Zhao; F. He; Y. -Q. Liu; J. -J. Yu; Z. -M. Ou; L. Ding; X. Chen; Z. -Y. Huang; M. Huang; S. -F. Zhou Pages 465 – 481 Abstract \| References \| Full Text PDF \| Full Text HTML \| Request Permissions Related Articles	buy now
	Prediction of metabolic clearance of diclofenac in adjuvant-induced arthritis rats using a substrate depletion assay S. Uno; A. Fujii; H. Komura; A. Kawase; M. Iwaki Pages 482 – 495 Abstract \| References \| Full Text PDF \| Full Text HTML \| Request Permissions Related Articles	buy now
	*In vitro* drug–drug interaction studies with febuxostat, a novel non-purine selective inhibitor of xanthine oxidase: plasma protein binding, identification of metabolic enzymes and cytochrome P450 inhibition M. Mukoyoshi; S. Nishimura; S. Hoshide; S. Umeda; M. Kanou; K. Taniguchi; H. Muroga Pages 496 – 510 Abstract \| References \| Full Text PDF \| Full Text HTML \| Request Permissions Related Articles	buy now
Clinical Pharmacokinetics and Metabolism
	Pharmacokinetics and metabolism of KW-4490, a selective phosphodiesterase 4 inhibitor: Difference in excretion of KW-4490 and acylglucuronide metabolites between rats and cynomolgus monkeys K. Fujita; H. Kodaira; T. Kuwabara; H. Kobayashi Pages 511 – 526 Abstract \| References \| Full Text PDF \| Full Text HTML \| Request Permissions Related Articles	buy now
	Comparative evaluation of absorption, distribution, and excretion of YM758, a novel If channel inhibitor, between albino and non-albino rats K. -I. Umehara; K. Seya; T. Sonoda; E. Nakamura; K. Noguchi; T. Usui; H. Kamimura Pages 527 – 539 Abstract \| References \| Full Text PDF \| Full Text HTML \| Request Permissions Cited By \| Related Articles	buy now
	Metabolism of prazosin in rat and characterization of metabolites in plasma, urine, faeces, brain and bile using liquid chromatography/mass spectrometry (LC/MS) J. C. L. Erve; S. C. Vashishtha; O. Ojewoye; A. Adedoyin; R. Espina; W. DeMaio; R. E. Talaat Pages 540 – 558 Abstract \| References \| Full Text PDF \| Full Text HTML \| Request Permissions Cited By \| Related Articles	buy now