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Drug Metabolism Reviews
, Volume
40
Issue 2 2008
Official Journal of the International Society for the Study of Xenobiotics
2007 Impact Factor: 5.579 (© Thomson Scientific, Journal Citation Reports®, 2008)
ISSN:
1097-9883 (electronic) 0360-2532 (paper)
Publication Frequency:
4 issues per year
Subjects:
Pharmacokinetics
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Toxicology
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Informa Healthcare
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Preface
Preface
Allan E. Rettie
Page 185
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From Human Genetics and Genomics to Pharmacogenetics and Pharmacogenomics: Past Lessons, Future Directions
Daniel W. Nebert; Ge Zhang; Elliot S. Vesell
Pages 187 – 224
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A Genomic “Roadmap” to “Better” Drugs
Guochun Liao; Xun Zhang; David J. Clark; Gary Peltz
Pages 225 – 239
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The Environmental Genome Project: Reference Polymorphisms for Drug Metabolism Genes and Genome-Wide Association Studies
Mark J. Rieder; Robert J. Livingston; Ian B. Stanaway; Deborah A. Nickerson
Pages 241 – 261
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Regulatory Polymorphisms and their Contribution to Interindividual Differences in the Expression of Enzymes Influencing Drug and Toxicant Disposition
Ronald N. Hines; Sevasti B. Koukouritaki; Mark T. Poch; Michael C. Stephens
Pages 263 – 301
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Cancer Pharmacogenomics: DNA Genotyping and Gene Expression Profiling to Identify Molecular Determinants of Chemosensitivity
J. Todd Auman; Howard L. McLeod
Pages 303 – 315
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Pharmacogenomics of MRP Transporters (ABCC1-5) and BCRP (ABCG2)
Ulrike Gradhand; Richard B. Kim
Pages 317 – 354
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Pharmacogenomics of 4-Hydroxycoumarin Anticoagulants
Nicholas Au; Allan E. Rettie
Pages 355 – 375
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A Review of Public Policy Issues in Promoting the Development and Commercialization of Pharmacogenomic Applications: Challenges and Implications
Louis P. Garrison Jr.; Rick J. Carlson; Josh J. Carlson; Patricia C. Kuszler; Lisa M. Meckley; David L. Veenstra
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