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Cancer Investigation, Volume 26 Issue 5 2008

Cancer Investigation is moving!
ISSN: 1532-4192 (electronic) 0735-7907 (paper)
Publication Frequency: 10 issues per year
Subject: Oncology;
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SPECIAL ARTICLE
Clinical Trials of Novel and Targeted Therapies: Endpoints, Trial Design, and Analysis
Vera J. Suman;  Amylou Dueck; Daniel J. Sargent
Pages 439 – 444
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COMMENTARY
The Emperor's New Clothes or the Current Practice of Clinical Trials for Multiple Myeloma in the USA
Oscar Ballester
Pages 445 – 447
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ORIGINAL ARTICLE/Cellular and Molecular Biology
Targeting Toll-Like Receptor 9 with CpG Oligodeoxynucleotides Enhances Anti-Tumor Responses of Peripheral Blood Mononuclear Cells from Human Lung Cancer Patients
Tao Ren *;  Zhen-Ke Wen *;  Zhong-Min Liu;  Cheng Qian;  Yong-Jie Liang;  Mei-Ling Jin;  Ying-Yun Cai; Lin Xu
Pages 448 – 455
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The Expression of Bcl-XL, Bcl-XS and p27Kip1 in Topotecan-Induced Apoptosis in Hepatoblastoma HepG2 Cell Line
Jun Zhang;  Chao Cheng;  Chuang-Long He;  Yu-Jian Zhou; Yang Cao
Pages 456 – 463
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Plasminogen Derivatives Encoding Kringles 1-4 and Kringles 1-5 Exert Indirect Antiangiogenic and Direct Antitumoral Effects in Experimental Lung Cancer
Volker Schmitz;  Esther Raskopf;  Maria-Angeles Gonzalez-Carmona;  Annabelle Vogt;  Miroslaw Kornek;  Tilman Sauerbruch; Wolfgang H. Caselmann
Pages 464 – 470
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ORIGINAL ARTICLE/Clinical Translational Therapeutics
Impaired Lymphocyte Responses and Their Restoration in Oral Cancer Patients Expressing Distinct TCR Variable Region
Persis Wadia;  Dakshayini Rao;  Trupti Pradhan;  Alok Pathak; Shubhada Chiplunkar
Pages 471 – 480
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Reducing the Risk of Distant Metastases: A Better End Point in Adjuvant Aromatase Inhibitor Breast Cancer Trials?
Shou-Ching Tang
Pages 481 – 490
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Adjuvant Dose-Dense Sequential Chemotherapy with Epirubicin, CMF and Weekly Paclitaxel in Patients with Resected High-Risk Breast Cancer: A Hellenic Cooperative Oncology Group (HeCOG) Study
Christos A. Papadimitriou;  Pavlos Papakostas;  Eleni Timotheadou;  Gerasimos Aravantinos;  Aristotelis Bamias; George Fountzilas
Pages 491 – 498
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ORIGINAL ARTICLE/Imaging, Diagnosis, Prognosis
High Levels of Granzyme B Expression in Invasive Cervical Carcinoma Correlates to Poor Response to Treatment
Valeska B. Guzman;  Ismael D. C. G. Silva;  Sylvia M. F. Brenna;  Carmen R. N. Carvalho;  Julisa C. L. Ribalta; Maria Gerbase-DeLima
Pages 499 – 503
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ORIGINAL ARTICLE/Causation and Prevention
Validation of the Simplified Chinese Version of the Quality of Life Instrument EORTC QLQ-LC43 for Patients with Lung Cancer
Chonghua Wan;  Canzhen Zhang;  Xin Tu;  Changyong Feng;  Wan Tang;  Jiahong Luo; Qiong Meng
Pages 504 – 510
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The Risk of Hepatocellular Carcinoma in Patients with Previous Malignancy
Abby B. Siegel;  Russell B. McBride;  Hashem B. El-Serag;  Dawn Hershman;  Robert S. Brown Jr.;  Lydia Zablotska; Alfred I. Neugut
Pages 511 – 515
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REVIEW
Extracutaneous Malignant Melanomas
Mahmoud R. Hussein
Pages 516 – 534
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Expression of Multidrug Resistance Genes in Normal and Cancer Stem Cells
A. Shervington; C. Lu
Pages 535 – 542
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BOOK REVIEW
A Review of: “Choices in Breast Cancer Treatment: Medical Specialists and Cancer Survivors Tell You What You Need to Know”
K. D. Miller, Ed., The Johns Hopkins University Press: Baltimore, 2008; 416 pp. $18.95 paperback.

Christina I. Herold
Page 543
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