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Volume 38 Issue 9
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Xenobiotica
The fate and safety evaluation of foreign compounds in biological systems
, Volume
38
Issue 9 2008
ISSN:
1366-5928 (electronic) 0049-8254 (paper)
Publication Frequency:
12 issues per year
Subjects:
Pharmacology
;
Toxicology
;
Publisher:
Informa Healthcare
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Original Articles
In vitro
metabolism of a novel PPAR
γ
agonist, KR-62980, and its stereoisomer, KR-63198, in human liver microsomes and by recombinant cytochrome P450s
K. -B. Kim; K. -A. Seo; Y. -J. Yoon; M. -A. Bae; H. G. Cheon; J. -G. Shin; K. -H. Liu
Pages 1165 – 1176
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Involvement of stearoyl-CoA desaturase in the reduction of amidoxime prodrugs
R. Reh; J. Ozols; B. Clement
Pages 1177 – 1190
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Characterization of renal tubular apical efflux of zonampanel, an
α
-amino-3-hydroxy-5- methylisoxazole-4-propionate receptor antagonist, in humans
T. Minematsu; T. Hashimoto; T. Usui; H. Kamimura
Pages 1191 – 1202
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Effect of cationic drugs on the transporting activity of human and rat OCT/Oct 1–3
in vitro
and implications for drug–drug interactions
K. -I. Umehara; T. Iwatsubo; K. Noguchi; T. Usui; H. Kamimura
Pages 1203 – 1218
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Strategies to prevent
N
-acetyltransferase-mediated metabolism in a series of piperazine-containing pyrazalopyrimidine compounds
J. Rawal; R. Jones; A. Payne; I. Gardner
Pages 1219 – 1239
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Contribution of cytochrome P450 3A4 and 3A5 to the metabolism of atorvastatin
J. -E. Park; K. -B. Kim; S. K. Bae; B. -S. Moon; K. -H. Liu; J. -G. Shin
Pages 1240 – 1251
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Genetic variants of organic cation transporter 2 (OCT2) significantly reduce metformin uptake in oocytes
I. S. Song; H. J. Shin; J. G. Shin
Pages 1252 – 1262
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