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Xenobiotica The fate and safety evaluation of foreign compounds in biological systems, Volume 38 Issue 9 2008

Xenobiotica is moving!

ISSN: 1366-5928 (electronic) 0049-8254 (paper)
Publication Frequency: 12 issues per year
Subjects: Pharmacology; Toxicology;
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Original Articles
In vitro metabolism of a novel PPARγ agonist, KR-62980, and its stereoisomer, KR-63198, in human liver microsomes and by recombinant cytochrome P450s
K. -B. Kim;  K. -A. Seo;  Y. -J. Yoon;  M. -A. Bae;  H. G. Cheon;  J. -G. Shin; K. -H. Liu
Pages 1165 – 1176
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Involvement of stearoyl-CoA desaturase in the reduction of amidoxime prodrugs
R. Reh;  J. Ozols; B. Clement
Pages 1177 – 1190
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Characterization of renal tubular apical efflux of zonampanel, an α-amino-3-hydroxy-5- methylisoxazole-4-propionate receptor antagonist, in humans
T. Minematsu;  T. Hashimoto;  T. Usui; H. Kamimura
Pages 1191 – 1202
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Effect of cationic drugs on the transporting activity of human and rat OCT/Oct 1–3 in vitro and implications for drug–drug interactions
K. -I. Umehara;  T. Iwatsubo;  K. Noguchi;  T. Usui; H. Kamimura
Pages 1203 – 1218
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Strategies to prevent N-acetyltransferase-mediated metabolism in a series of piperazine-containing pyrazalopyrimidine compounds
J. Rawal;  R. Jones;  A. Payne; I. Gardner
Pages 1219 – 1239
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Contribution of cytochrome P450 3A4 and 3A5 to the metabolism of atorvastatin
J. -E. Park;  K. -B. Kim;  S. K. Bae;  B. -S. Moon;  K. -H. Liu; J. -G. Shin
Pages 1240 – 1251
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Genetic variants of organic cation transporter 2 (OCT2) significantly reduce metformin uptake in oocytes
I. S. Song;  H. J. Shin; J. G. Shin
Pages 1252 – 1262
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