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Xenobiotica The fate and safety evaluation of foreign compounds in biological systems, Volume 38 Issue 11 2008

Xenobiotica is moving!

Linked to the International Society for the Study of Xenobiotics
ISSN: 1366-5928 (electronic) 0049-8254 (paper)
Publication Frequency: 12 issues per year
Subjects: Pharmacology; Toxicology;
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Obituary
David McKillop BSc, PhD 1951–2008
Pages 1353 – 1354
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Original Articles
Human CYP3A4-introduced HepG2 cells: In vitro screening system of new chemicals for the evaluation of CYP3A4-inhibiting activity
N. Araki;  S. Tsuruoka;  N. Wang;  G. Hasegawa;  H. Yanagihara;  H. Ando;  T. Omasa;  S. Enosawa;  H. Nagai; A. Fujimura
Pages 1355 – 1364
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Lack of interaction between metoclopramide and morphine in vitro and in mice
D. Ung;  A. Cowan;  H. P. Parkman; S. Nagar
Pages 1365 – 1376
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Interspecies scaling of a camptothecin analogue: Human predictions for intravenous topotecan using animal data
P. Ahlawat; N. R. Srinivas
Pages 1377 – 1385
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Determination of microsome and hepatocyte scaling factors for in vitro/in vivo extrapolation in the rat and dog
R. Smith;  R. D. O. Jones;  P. G. Ballard; H. H. Griffiths
Pages 1386 – 1398
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Pharmacokinetics of bicyclol in rats with acute hepatic failure
Wei Tan;  Baolian Wang;  Jing Zhao;  Li Sheng;  Jinping Hu; Yan Li
Pages 1399 – 1409
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Impaired intrinsic chiral inversion activity of ibuprofen in rats with adjuvant-induced arthritis
S. Uno;  M. Uraki;  H. Komura;  H. Ikuta;  A. Kawase; M. Iwaki
Pages 1410 – 1421
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Influence of uridine diphosphate (UDP)-glucuronosyltransferases and ABCC2 genetic polymorphisms on the pharmacokinetics of mycophenolic acid and its metabolites in Chinese renal transplant recipients
W. -X. Zhang;  B. Chen;  Z. Jin;  Z. Yu;  X. Wang;  H. Chen;  A. Mao; W. Cai
Pages 1422 – 1436
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Assessing and minimizing time-dependent inhibition of cytochrome P450 3A in drug discovery: A case study with melanocortin-4 receptor agonists
W. Tang;  R. A. Stearns;  R. W. Wang;  R. R. Miller;  Q. Chen;  J. Ngui;  R. K. Bakshi;  R. P. Nargund;  D. C. Dean; T. A. Baillie
Pages 1437 – 1451
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