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Volume 38 Issue 12
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Xenobiotica
The fate and safety evaluation of foreign compounds in biological systems
, Volume
38
Issue 12 2008
ISSN:
1366-5928 (electronic) 0049-8254 (paper)
Publication Frequency:
12 issues per year
Subjects:
Pharmacology
;
Toxicology
;
Publisher:
Informa Healthcare
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Original Articles
Purification, molecular cloning, heterologous expression and characterization of pig CYP1A2
A. Messina; V. Chirulli; P. G. Gervasi; V. Longo
Pages 1453 – 1470
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Increased distribution of carboplatin, an anti-cancer agent, to rat brains with the aid of hyperbaric oxygenation
Y. Suzuki; K. Tanaka; D. Neghishi; M. Shimizu; N. Murayama; T. Hashimoto; H. Yamazaki
Pages 1471 – 1475
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In vivo
metabolism of
α
-methyltryptamine in rats: Identification of urinary metabolites
T. Kanamori; K. Kuwayama; K. Tsujikawa; H. Miyaguchi; Y. T. Iwata; H. Inoue
Pages 1476 – 1486
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Expression of a skin cholesterol sulfotransferase, St2b2, is a trigger of epidermal cell differentiation
M. Shimada; T. Matsuda; A. Sato; T. Akase; T. Matsubara; K. Nagata; Y. Yamazoe
Pages 1487 – 1499
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Efficient assessment of the utility of immortalized Fa2N-4 cells for cytochrome P450 (CYP) induction studies using multiplex quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR) and substrate cassette methodologies
J. R. Kenny; L. Chen; D. F. McGinnity; K. Grime; K. M. Shakesheff; B. Thomson; R. Riley
Pages 1500 – 1517
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Toward an improved prediction of human
in vivo
brain penetration
S. G. Summerfield; A. J. Lucas; R. A. Porter; P. Jeffrey; R. N. Gunn; K. R. Read; A. J. Stevens; A. C. Metcalf; M. C. Osuna; P. J. Kilford; J. Passchier; A. D. Ruffo
Pages 1518 – 1535
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Effects of dietary flavonoids on the transport of cimetidine via P-glycoprotein and cationic transporters in Caco-2 and LLC-PK1 cell models
J. -S. Taur; R. Rodriguez-Proteau
Pages 1536 – 1550
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Characterization of triptolide hydroxylation by cytochrome P450 in human and rat liver microsomes
W. Li; Y. Liu; Y. -Q. He; J. -W. Zhang; Y. Gao; G. -B. Ge; H. -X. Liu; H. Huo; H. -T. Liu; L. -M. Wang; J. Sun; Q. Wang; L. Yang
Pages 1551 – 1565
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