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Xenobiotica The fate and safety evaluation of foreign compounds in biological systems, Volume 39 Issue 2 2009

Xenobiotica is moving!

ISSN: 1366-5928 (electronic) 0049-8254 (paper)
Publication Frequency: 12 issues per year
Subjects: Pharmacology; Toxicology;
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Research Article
Validation of cytochrome P450 time-dependent inhibition assays: a two-time point IC50 shift approach facilitates kinact assay design
E. S. Perloff;  A. K. Mason;  S. S. Dehal;  A. P. Blanchard;  L. Morgan;  T. Ho;  A. Dandeneau;  R. M. Crocker;  C. M. Chandler;  N. Boily;  C. L. Crespi; D. M. Stresser
Pages 99 – 112
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Pharmacokinetics and disposition of recombinant human osteoprotegerin (rhOPG) after intravenous administration in female fischer rats
Y. Miyaji;  A. Kurihara;  E. Kamiyama;  T. Shiiki;  K. Kawai; O. Okazaki
Pages 113 – 124
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Pharmacokinetics of recombinant human soluble thrombomodulin, thrombomodulin alfa in the rat
K. Tsuruta;  T. Kodama;  M. Serada;  K. Hori;  A. Inaba;  T. Miyake; T. Kohira
Pages 125 – 134
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Pharmacokinetic interaction between efavirenz and ketoconazole in rats
A. Saadeddin; J. E. Peris
Pages 135 – 139
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Functional characterization of CYP3A4.16: Catalytic activities toward midazolam and carbamazepine
K. Maekawa;  T. Yoshimura;  Y. Saito;  Y. Fujimura;  F. Aohara;  C. Emoto;  K. Iwasaki;  N. Hanioka;  S. Narimatsu;  T. Niwa; J. Sawada
Pages 140 – 147
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In vitro and in vivo phase II metabolism of combretastatin A-4: Evidence for the formation of a sulphate conjugate metabolite
S. Aprile;  E. Del Grosso; G. Grosa
Pages 148 – 161
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Effect of ursodeoxycholic acid on the pharmacokinetics of midazolam and CYP3A in the liver and intestine of rats
S. Kurosawa;  S. Uchida;  Y. Ito,; S. Yamada
Pages 162 – 170
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Involvement of Mrp2/MRP2 in the species different excretion route of benzylpenicillin between rat and human
M. -K. Choi;  H. Kim;  Y. -H. Han;  I. -S. Song; C. -K. Shim
Pages 171 – 181
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Role of hepatitis B virus X repression of C/EBPβ activity in the down-regulation of glutathione S-transferase A2 gene: implications in other phase II detoxifying enzyme expression
I. J. Cho;  S. H. Ki;  C. Brooks III; S. G. Kim
Pages 182 – 192
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