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Xenobiotica The fate and safety evaluation of foreign compounds in biological systems, Volume 39 Issue 6 2009

Xenobiotica is moving!

Linked to the International Society for the Study of Xenobiotics
ISSN: 1366-5928 (electronic) 0049-8254 (paper)
Publication Frequency: 12 issues per year
Subjects: Pharmacology; Toxicology;
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Research Article
Cocktail-substrate assay system for mechanism-based inhibition of CYP2C9, CYP2D6, and CYP3A using human liver microsomes at an early stage of drug development
K. Mori;  H. Hashimoto;  H. Takatsu;  M. Tsuda-Tsukimoto; T. Kume
Pages 415 – 422
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Tissue distribution of CYP3A29 mRNA expression in Bama miniature pig by quantitative reverse transcriptase-polymerase chain reaction (RT-PCR)
H. Shang;  J. Yang;  Y. Liu; H. Wei
Pages 423 – 429
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Method for predicting the risk of drug–drug interactions involving inhibition of intestinal CYP3A4 and P-glycoprotein
T. Tachibana;  M. Kato;  T. Watanabe;  T. Mitsui; Y. Sugiyama
Pages 430 – 443
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In vitro metabolism of the specific endothelin-A receptor antagonist ZD4054 and clinical drug interactions between ZD4054 and rifampicin or itraconazole in healthy male volunteers
H. C. Swaisland;  S. D. Oliver;  T. Morris;  H. K. Jones;  A. Bakhtyari;  A. Mackey;  A. D. McCormick;  D. Slamon;  J. A. Hargreaves;  A. Millar; M. T. Taboada
Pages 444 – 456
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Pharmacokinetics of 20(S)-25-methoxyl-dammarane-3β, 12β, 20-triol and its active metabolite after oral and intravenous administration in rat
X. Zhang;  J. Xu;  D. Zhang;  J. Gu; Y. Zhao
Pages 457 – 464
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Pharmacokinetics and first-pass effects of liquiritigenin in rats: low bioavailability is primarily due to extensive gastrointestinal first-pass effect
H. E. Kang;  Y. K. Cho;  H. Y. Jung;  K. Y. Choi;  S. I. Sohn;  S. R. Baek; M. G. Lee
Pages 465 – 475
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Pharmacokinetic studies of enantiomers of ibuprofen and its chiral metabolites in humans with different variants of genes coding CYP2C8 and CYP2C9 isoenzymes
M. Karaźniewicz-łada;  M. łuczak; F. Główka
Pages 476 – 485
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