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Xenobiotica The fate and safety evaluation of foreign compounds in biological systems, Volume 39 Issue 9 2009

Xenobiotica is moving!

ISSN: 1366-5928 (electronic) 0049-8254 (paper)
Publication Frequency: 12 issues per year
Subjects: Pharmacology; Toxicology;
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Research Article
Prediction of Phase I single-dose pharmacokinetics using recombinant cytochromes P450 and physiologically based modelling
C. R. Gibson;  A. Bergman;  P. Lu;  F. Kesisoglou;  W. S. Denney; E. Mulrooney
Pages 637 – 648
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Species differences for stereoselective metabolism of ethofumesate and its enantiomers in vitro
W. Zhu;  Z. Dang;  J. Qiu;  Y. Liu;  C. Lv;  J. Diao; Z. Zhou
Pages 649 – 655
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Comparison of intrinsic metabolic clearance in fresh and cryopreserved human hepatocytes
E. Floby;  J. Johansson;  J. Hoogstraate;  N. J. Hewitt;  J. Hill; A. -K. Sohlenius-Sternbeck
Pages 656 – 662
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Cytochrome P450-catalysed arene-epoxidation of the bioactive tea tree oil ingredient p-cymene: indication for the formation of a reactive allergenic intermediate?
R. J. W. Meesters;  M. Duisken; J. Hollender
Pages 663 – 671
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CYP1A2 is the major isoform responsible for paeonol O-demethylation in human liver microsomes
H. -X. Liu;  Y. Hu;  Y. Liu;  Y. -Q. He;  W. Li; L. Yang
Pages 672 – 679
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Flavin-containing monooxygenase 1-catalysed N,N-dimethylamphetamine N-oxidation
S. K. Lee;  M. J. Kang;  C. Jin;  M. K. In;  D. -H. Kim; H. H. Yoo
Pages 680 – 686
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Utility of unbound plasma drug levels and P-glycoprotein transport data in prediction of central nervous system exposure
H. He;  K. A. Lyons;  X. Shen;  Z. Yao;  K. Bleasby;  G. Chan;  M. Hafey;  X. Li;  S. Xu;  G. M. Salituro;  L. H. Cohen; W. Tang
Pages 687 – 693
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Effect of continuous silymarin administration on oral talinolol pharmacokinetics in healthy volunteers
Y. Han;  D. Guo;  Y. Chen;  Z. -R. Tan; H. -H. Zhou
Pages 694 – 699
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Disposition of GDC-0879, a B-RAF kinase inhibitor in preclinical species
E. F. Choo;  J. P. Driscoll;  J. Feng;  B. Liederer;  E. Plise;  N. Randolph;  Y. Shin;  S. Wong; Y. Ran
Pages 700 – 709
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